Polymorphism G-105A SEPS1 gene and mens’ infertility
نویسندگان
چکیده
منابع مشابه
The SEPS1 G-105A Polymorphism Is Associated with Risk of Spontaneous Preterm Birth in a Chinese Population
Inflammation plays an important role in the etiology and pathophysiology of spontaneous preterm birth (SPTB), and selenoprotein S (SEPS1) is involved in regulating the inflammatory response. Recently the G-105A promoter polymorphism in SEPS1 was shown to increase pro-inflammatory cytokine expression. We examined whether this functional polymorphism was related to the risk of SPTB in a Chinese p...
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Background & Objective: Host resistance to Leishmania infection is mediated by cellular immune responses leading to macrophage activation and parasite killing. IL-18 known as interferon-γ inducing factor, stimulate IFN-γ production by T-cells. According to the important role of IL-18 in defense against VL and known effect of IL-18 gene polymorphisms on its production, the aim of this study was ...
متن کاملThe POLG Gene Polymorphism in Iranian Varicocele-Associated Infertility Patients
Objective(s) Varicocele is associated with impaired testicular function and male infertility, but the molecular mechanisms by which fertility is affected have not been satisfactorily explained. The aim of our study was to investigate whether or not the polymerase gamma (POLG) polymorphism is associated with Iranian varicocele patients. Materials and Methods We determined the POLG CAG repe...
متن کاملInterleukin-18 gene 105A/C genetic polymorphism is associated with the susceptibility of Kawasaki disease.
Interleukin-18 (IL-18)-656T/G, -607A/C, and -137C/G promoter polymorphisms had been reported associated with Kawasaki disease (KD). An IL-18 genetic A/C polymorphism at coding position 105 (rs549908) has been linked with asthma, rheumatoid, and systemic lupus erythematosus. We tested a hypothesis that the IL-18 105A/C genetic polymorphism confers KD susceptibility. Study participants were Taiwa...
متن کاملPolymorphism of the estrogen receptor β gene is related to infertility and infertility-associated endometriosis.
OBJECTIVE To determine the frequency of the estrogen receptor b gene (ERβ) +1730 G/A polymorphism in infertile women with and without endometriosis and controls. SUBJECTS AND METHODS Case-control study that included 136 women with endometriosis, 69 women without endometriosis and 209 fertile women as controls. The ERβ gene + 1730 G/A polymorphism was identified by RFLP-PCR (Restriction Fragme...
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ژورنال
عنوان ژورنال: Medical news of the North Caucasus
سال: 2018
ISSN: 2073-8137
DOI: 10.14300/mnnc.2018.13085